Scientific Programme

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UKKW 2017 Full Printable Version of the Programme

Please note timings are approximate and are subject to change.

Time Title
08:00 Registration Opens
Location: Hall 2B

09:00 - 10:45 Special Session: UKKW 2017 Opening; AKI Session including ISN talk by John Feehally
Location: Hall 1


Acute Kidney Injury - a Global Challenge
Professor John Feehally, University Hospitals Leicester, United Kingdom
Improving AKI Care in Malawi
Rhys Evans, University College London, United Kingdom
AKI and the Promise of Regenerative Medicine
Dr Sanjeev Kumar, Regenerative Medicine Institute, Cedars Sinai Medical Center, USA
Novel Insights into Immune-Mediated AKI
Meena Clatworthy, University of Cambridge and Addenbrookes Hospital, United Kingdom
AKI as a cause of CKD: What is the scale of the problem and what can we do about it?
Dr Nick Selby, University of Nottingham and Royal Derby Hospital, United Kingdom
10:45 - 11:15 Morning Coffee Break / Exhibition
Location: Hall 2B

11:15 - 12:45 Parallel Session: 3 Minute Heroes
Chairs:
Location: Hall 1A


Title - TBC
Richard Coward, University of Bristol, United Kingdom
Increasing insulin receptor number protects podocytes from ER stress
Dr Kathryn Garner, University of Bristol, United Kingdom
New therapeutic targets in proteinase-3 induced granuloma formation in granulomatosis with polyangiitis
Dr Scott Henderson, University College London, United Kingdom
Podocyte glycogen synthase kinase 3 (GSK3) is an evolutionarily conserved master regulator of glomerular/excretory function controlling podocyte differentiation and cell cycling
Dr Jenny Hurcombe, University of Bristol, United Kingdom
microRNA Regulation of Macrophage Phenotype in Peritoneal Fibrosis
Dr Robert Jenkins, Cardiff University, United Kingdom
Th17 Cells and Podocyte Crosstalk
Carl May, University of Bristol, United Kingdom
Connective Tissue Growth Factor (CTGF) is a Critical Mediator of Cryoglobulinaemic Vasculitis (CV) and a novel target for therapy
Dr Gayathri Rajakaruna, University College London, United Kingdom
Human kidney-derived cells ameliorate acute kidney injury without engrafting into renal tissue
Dr Ilaria Santeramo, University of Liverpool, United Kingdom
Human Urine Derived Renal Tubular Epithelial Cells (HURECs) reveal a novel ciliary phenotype for CEP290 ciliopathies and serve as readout for identification of novel therapies for nephronophthisis
Dr Shalabh Srivastava, Newcastle University, United Kingdom
Systemic administration of stem cells via the left heart ventricle enables their efficient delivery to the kidneys
Dr Arthur Taylor, University of Liverpool, United Kingdom
Proof that mesothelial cells directly contribute to peritoneal scars in vivo
Dr Thomas Wilm, University of Liverpool, United Kingdom
MicroRNA-200c Inhibits TGF-β1-induced Epithelial-to-mesenchymal Transition and Fibrogenesis in Human Peritoneal Mesothelial Cells
Dr Susan Yung, The University of Hong Kong, Hong Kong
11:15 - 12:45 Parallel Session: CKD
Chairs:
Location: Hall 1B


Evolving anti-fibrotic therapies in Chronic Kidney Disease
Professor Donald Fraser, University Hospital of Wales, United Kingdom
SGLT-2 Inhibitors as potential renal protective therapy?
Professor David Wheeler, University College London, United Kingdom
Urinary endotrophin is associated with CKD progression at 12 months: a prospective observational study
Dr Anthony Fenton, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
Multiparametric Magnetic Resonance Imaging Assessment of Chronic Kidney Disease
Dr Huda Mahmoud, Centre for Kidney Research and Innovation, United Kingdom
Mesenchymal Stromal Cells for Diabetic Kidney Disease: Bench to Bedside
Professor Timothy O'Brien, Regenerative Medicine Institute (REMEDI), Republic of Ireland
11:15 - 12:45 Parallel Session: Comparative Veterinary Nephrology
Chairs:
Location: Hall 1C


What do we know about normal renal function in dogs and cats?
Professor Scott Brown, University of Georgia, USA
Renal disease in cats and dogs
Professor Hattie Syme, Royal Veterinary College, United Kingdom
Clinical issues and opportunities confronting both veterinary and human nephrology
Professor Jonathan Elliot, Royal Veterinary College, United Kingdom
Clinical issues and opportunities confronting both veterinary and human nephrology
Dr Thomas Hiemstra, University of Cambridge, United Kingdom
12:45 - 14:15 Lunch Break / Exhibition
Location: Hall 5

12:45 - 14:15 Afternoon Corporate Session with Vifor Fresenius
Location:

12:45 - 14:15 Afternoon Corporate Session with Otsuka Pharmaceuticals
Location:

14:15 - 15:15 Moderated Poster Session
Chair:
Location: Hall 2B

15:15 - 15:45 Afternoon Coffee Break / Exhibition
Location: Hall 2B

15:45 - 17:30 Parallel Session: 21st Century Communications
Chairs:
Location: Hall 1A


The Healthcare in Social Media Report: A multi-media social network and communication project
Richard McCrory
Clinical trial and research communication in the 21st Century: A strategy in partnership with Kidney Research UK
Tom Oates, NephJC, United Kingdom
The Renal Fellow Network: A renal education blog for fellows, by fellows
Paul Phelan
Royal Infirmary of Edinburgh, United Kingdom
Patient use of social networks for information and peer support
Robert Finnigan, British Kidney Patient Association, United Kingdom
The use of Social Media to identify and respond to unmet patient needs
Cristina Vasillica
15:45 - 17:30 Parallel Session: Basic Science
Chairs:
Location: Hall 1B


Title - TBC
Dr Nick Selby, University of Nottingham, United Kingdom
Gdf11 is induced in the murine and human kidney in response to injury, with experimental administration worsening fibrosis after unilateral ureteric obstruction.
Dr David Ferenbach, University of Edinburgh, United Kingdom
Urinary trace elements as novel biomarkers of ischaemic acute kidney injury: Data from porcine model
Professor David Gardner, University of Nottingham, United Kingdom
Title - TBC
Professor Donald Fraser, University Hospital of Wales, United Kingdom
15:45 - 17:30 Parallel Session: ESKD
Chairs:
Location: Hall 1C


How can the registry improve outcomes for renal patients in the UK
Fergus Caskey
Can we control volume sufficiently in anuric patients?
Simon Davies
Tailoring HD prescriptions to improve outcomes
James Tattersall
Stroke in Haemodialysis (HD): Using National Datasets to determine incidence, Risk factors & Outcomes
Dr Mark Findlay, University of Glasgow, United Kingdom
In-center nocturnal haemodialysis is associated with favourable cardiac remodeling and reduced levels of myocardial fibrosis: Results from the MIDNIGHT study, a non-randomised controlled trial
Dr Matthew Graham-Brown, University Hospitals Leicester, United Kingdom
Associations between haemodialysis facility practices related to fluid volume management and intra-dialytic hypotension and adverse outcomes in the DOPPS
Dr Indranil Dasgupta, Heart of England NHS Foundation Trust, United Kingdom
17:30 - 18:00 Special Session: Summary of the Day
Location: Hall 1A

18:30 - 19:30 Kidney Research UK Hosted Fun Run
Please note registration commences at 18:00

19:00 - 21:00 Renal Association Presidential Address
Location: Hall 2B


Time Title
07:00 Registration Opens
Location: Hall 2B
07:45 - 08:45 Morning Corporate Session with Kidney Research UK and National Institute for Health Research
Location:
09:00 - 10:45 Parallel Session: CKD inc ISN talk by Adeera Levin
Chairs:
Location: Hall 1A

Opportunities and challenges to improve outcomes in CKD around the world
Professor Adeera Levin, University of British Columbia, Canada
The effects a of 12-week supervised aerobic or combined exercise programme on muscle size, strength, and physical performance in non-dialysis CKD patients
Douglas Gould, University of Leicester, United Kingdom
Coding for Chronic Kidney Disease: risk factors, audit-related improvement, and patient management. Results from the National Chronic Kidney Disease Audit
Dr Lois Kim, London School of Hygiene and Tropical Medicine, United Kingdom
Blood Pressure Targets in CKD: Did SPRINT give us the answers or are we still on a marathon to find them?
Richard Haynes, Nuffield Department of Population Health, United Kingdom
NURTuRE CKD: a national bio-clinical cohort study
Professor Maarten Taal, University of Nottingham, United Kingdom
09:00 - 10:45 Parallel Session: General Nephrology
Chairs:
Location: Hall 1B

Title - TBC
Clara Day

Title - TBC
Fiona Loud, British Kidney Patient Association, United Kingdom
UKRRS which arose from ambition 15 of the above
Professor John Feehally, University Hospitals Leicester, United Kingdom
Iron deficiency and the Heart in CKD - Beyond Haemoglobin
Professor Sunil Bhandari, Hull York Medical School, United Kingdom
09:00 - 10:45 Parallel Session: Research Masterclass
Chairs:
Location: Hall 1C

So you want to become involved in clinical research, but don’t have time to do it
Iain Macdougall, King's College Hospital NHS Foundation Trust, United Kingdom
The story of cholesterol-lowering in CKD: from hypothesis to meta-analysis
Colin Baigent, University of Oxford, United Kingdom
I've got a hypothesis - how do I test it?
Dr Thomas Hiemstra, University of Cambridge, United Kingdom
10:45 - 11:15 Morning Coffee Break / Exhibition
Location: Hall 2B
11:15 - 12:45 Parallel Session: Glomerulonephritis
Chairs:
Location: Hall 1A

IgA nephropathy – current concepts and knowledge
Dr Jonathan Barratt, Leicester General Hospital, United Kingdom
Syk Inhibitors and IgA nephropathy
Professor Fred Tam, Imperial College, United Kingdom
MicroRNA inIgA nephropathy and CKD – Novel Biomarkers and Targets
Dr Laura Denby, University of Edinburgh, United Kingdom
11:15 - 12:45 Parallel Session: Clinical Trials
Chairs:
Location: Hall 1B

Current RCTs in UK nephrology
Professor Phil Kalra, Salford Royal Hospital NHS Foundation Trust, United Kingdom
Using national registries to collect outcomes in trials
Fergus Caskey, University of Bristol, United Kingdom
SGLT2i in CKD - what have we learnt from EMPA-REG
Paddy Mark, University of Glasgow, United Kingdom
Which outcomes should we use in nephrology trials?
Will Herrington, University of Oxford, United Kingdom
11:15 - 12:45 Parallel Session: OOP Opportunities for Trainees
Chairs:
Location: Hall 1C

Eoin McKinney, University of Cambridge, United Kingdom
Amanda Newnham, Leeds Teaching Hospitals NHS Trust, United Kingdom
Carolyn Amery, United Kingdom
12:45 - 14:15 Lunch Break / Exhibition
Location: Hall 5
12:45 - 14:15 Afternoon Corporate Session with Vifor Fresenius
Location:
12:45 - 14:15 Afternoon Corporate Session with Janssen, Pharmaceutical Companies of Johnson and Johnson
Location:
14:15 - 15:15 Moderated Poster Session
Chair:
Location: Hall 2B
14:45 - 15:45 Renal Association AGM
Location:

15:15 - 15:45 Afternoon Coffee Break / Exhibition
Location: Hall 2B
15:45 - 17:30 Parallel Session: AKI
Chairs:
Location: Hall 1A

Live imaging in AKI: novel insights into mechanisms of injury and repair
Andrew Hall, University of Zurich, Switzerland
AKI and organ cross talk: Does AKI harm other organ systems?
Mark Devonald, Nottingham University Hospitals, United Kingdom
Biomarkers in AKI: Where are we now?
Andrew Lewington, University of Leeds Teaching Hospitals, United Kingdom
Sepsis-associated AKI: A global threat to kidney health?
Chris Laing, Royal Free Hospital/University College London, United Kingdom
Acute kidney injury in elective surgery: reducing the incidence with pre-operative risk assessment and post-operative monitoring
Professor Dr Christopher Wong, Aintree University Hospital, United Kingdom
Urinary trace elements as biomarkers of acute kidney injury after intensive care unit admission
Dr Jennifer Allen, Nottingham University Hospitals NHS Trust, United Kingdom
15:45 - 17:30 Parallel Session: Young Investigator
Chairs:
Location: Hall 1B

Evaluation of a cannabinoid receptor (CNR1) antagonist/ CNR2 agonist on podocyte markers in a mouse model of experimental diabetes
Dr Ruth Banks, University of Aberdeen, United Kingdom
Identification of novel NUP93 mutations in SRNS and evidence for a functional role for this protein in the regulation of podocyte biology
Dr Agnieszka Bierzynska, University of Bristol, United Kingdom
Development of a refined subtotal nephrectomy mouse model to study progressive renal disease
Dr Laura Denby, University of Edinburgh, United Kingdom
Insect nephrocytes as a model for human podocyte ageing
Dr Paul Hartley, Bournemouth University, United Kingdom
Title - TBC
Professor Karl Kadler, The University of Manchester, United Kingdom
15:45 - 17:30 Parallel Session: KQuIP
Chairs:
Location: Hall 1C

KQuIP Update
Graham Lipkin
Teaching QI through hands on experience; LTMD
Emma Vaux
Transplant First: addressing access to transplantation
Kerry Tomlinson
How to improve access to home Therapies or Getting Right First Time
Patient Led Research Hub for Renal Research: a Progress Report
Dr Thomas Hiemstra, University of Cambridge, United Kingdom
Measuring Patient Activation and Quality of Life Outcomes - the experience of 10 renal units
Rachel Gair, UK Renal Registry, United Kingdom
Outcome data for Nephrology day case procedure undertaken by Advanced Nurse Practitioner to reduce cost and length of stay
Andrew Stott, Royal Liverpool Broadgreen Hospital, United Kingdom
Evaluation of a secondary care CKD email advice service for GPs in North West London
Dr Sameer Zaman, Imperial College London, United Kingdom
17:30 - 18:00 Special Session: Summary of the Day
Location: Hall 1A
18:00 - 19:00 SpR Club
Location: Hall 2B
19:30 - 23:59 Conference Dinner
Location: Royal Liver Building
Time Title
07:00 Registration Opens
Location: Hall 2B
09:00 - 10:45 Parallel Session: Transplant
Chairs:
Location: Hall 1A
Overview of living donation in the UK
Lisa Burnapp
Challenges facing living donation: Inequity of access
Diana Wu
Challenges facing living donation: Is it safe to be a living donor?
Rachel Hilton, Guy's and St Thomas' NHS Foundation Trust, United Kingdom
Case based discussion around a HSP
Nicholas Torpey, Addenbrookes Hospital, United Kingdom
How do we get living donation discussion up front? Transplant first-
Jen/Craig Lumsdaine
Will they donate? Predictors of non-donation and withdrawal in a UK multicentre prospective cohort study of potential living kidney donors
Dr Pippa Bailey, University of Bristol and North Bristol NHS Trust, United Kingdom
Recipient Age is a Significant Factor in Immunological and Infective Complications Following Kidney Transplantation
Dr Rachel Hung, Royal Free Hospitals NHS Foundation Trust, United Kingdom
09:00 - 10:45 Parallel Session: Renal Pharmacology
Chairs:
Location: Hall 1B
Personalising the prescription in the 21st Century
Professor Sir Munir Primohamed, University of Liverpool, United Kingdom
Nanomedicine: what should a Nephrologist know?
Dr Neill Liptrott, University of Liverpool, United Kingdom
Pharmacokinetics and renal impairment: how can we get it right?
Professor Amin Rostami, University of Manchester, United Kingdom
Screening for adrenal insufficiency prior to withdrawal of corticosteroid treatment for renal conditions: an audit cycle at a tertiary centre
Dr Alvin Karangizi, University Hospitals NHS Foundation Trust, United Kingdom
A Phase-Two, Randomised, Placebo-Controlled Trial: Belimumab in Renal Transplantation Targets Naïve and Activated Memory B Cells Whilst Sparing Regulatory B Cells
Dr Gemma Banham, University of Cambridge, United Kingdom
09:00 - 10:45 Parallel Session: Glomerulonephritis
Chairs:
Location: Hall 1C
What is new in Membranous Nephropathy?
Professor Paul Brenchley, University of Manchester, United Kingdom
Developing therapies for Vasculitis; from new targets to clinical studies
Professor Caroline Savage, GlaxoSmithKline, United Kingdom
PLA2R positive Membranous Nephropathy associated with viral infection
Dr Aikaterini Nikolopoulou, Imperial College London, United Kingdom
The RituxiRescue regimen (Rituximab, Mycophenolate Mofetil & no increase in oral steroids) for lupus nephritis leads to sustained disease remission over years and steroid minimisation in patients on maintenance steroids at the time of renal flare.
Dr Camilla Pillay, Imperial College Healthcare NHS Trust, United Kingdom
Rituximab is Highly Effective Treatment for Small Vessel Vasculitis in Absence of Circulating ANCA
Dr Leanne Ogden, NHS, United Kingdom
10:45 - 11:15 Morning Coffee Break / Exhibition
Location: Hall 2B
11:15 - 12:45 Parallel Session: ESKD inc ISN Debate
Chairs:
Location: Hall 1A
Towards improving global access to ESKD care : Investing resources in dialysis is a distraction
Vivek Jha, India
Quality of life in frail older people with end stage renal disease – How does dialysis compare with conservative kidney care?
Dr Osasuyi Iyasere, Leicester General Hospital, United Kingdom
Peritoneal Inflammation Increases Over Time, with Subsequent Increases in Plasma IL-6: Results From the Global Fluid Study
Dr Emma Elphick, Keele University, United Kingdom
Towards improving global access to ESKD care : Investing resources in dialysis is a distraction
Professor Dr W Van Bissen, Ghent University Hospital, Belgium
Incentre dialysis in the face of austerity - how to get the best?
Clara Day
11:15 - 12:45 Parallel Session: Transplant
Chairs:
Location: Hall 1B
Novel immunosuppressants: current and future?
Meena Clatworthy
Prevention of delayed graft function-current state of therapies
Lorna Marson, The University of Edinburgh, United Kingdom
Cell therapies in transplant-science fiction or reality?
Giovanna Lombardi, King's College London, United Kingdom
Clinical relevance of complement activating donor specific antibodies in highly sensitised patients: Two centre retrospective study
Dr Adarsh Babu, University Hospitals Coventry and Warwickshire, United Kingdom
Risk of allograft thrombosis and Use of Thrombophilia screen in high risk Kidney Transplant Recipients (KTRs) -A Single Centre Experience
Dr Rajkumar Chinnadurai, Salford Royal NHS Foundation Trust, United Kingdom
11:15 - 12:45 Parallel Session: Raine Award and Best Clinical Abstracts
Chairs:
Location: Hall 1C
AEG Raine Award 2017
Edwin Wong, Newcastle University, United Kingdom
Subclinical cytomegalovirus reactivation drives a reversible expansion of cytotoxic endothelial homing T-cells: a novel modifiable cardiovascular disease risk factor in patients with inflammatory renal disease
Dr Dimitrios Chanouzas, University of Birmingham, United Kingdom
Cognitive function declines significantly over a single haemodialysis session
Dr Indranil Dasgupta, Heart of England NHS Foundation Trust, United Kingdom
Diagnostic accuracy of biomarkers and imaging in predicting bone turnover in advanced chronic kidney disease
Dr Syazrah Salam, Sheffield Kidney Institute, Northern General Hospital, United Kingdom
The Impact of Cystatin C Based Estimates of GFR on CKD Diagnosis in Primary Care
Dr Adam Shardlow, Royal Derby Hospital, United Kingdom
Renal and Obstetric Outcomes of Pregnant Women with CKD 3-5
Dr Philip Webster, Imperial College London, United Kingdom
12:45 - 14:15 Lunch Break / Exhibition
Location: Hall 5
12:45 - 14:15 Afternoon Corporate Session with AbbVie
Location:
14:15 - 15:15 Moderated Poster Session
Chair:
Location: Hall 2B
15:15 - 15:45 Afternoon Coffee Break / Exhibition
Location: Hall 2B
15:45 - 17:30 Parallel Session: Clinico-pathologic Cases
Chairs:
Location: Hall 1A
Professor Jeremy Levy, Imperial College NHS Trust, United Kingdom
Nicholas Torpey, Addenbrookes Hospital, United Kingdom
Rachel Hilton, Guy's and St Thomas' NHS Foundation Trust, United Kingdom
Elizabeth Wallin, Addenbrookes Hospital, United Kingdom
Viyaasan Mahalingasivam, Guy's and St Thomas' NHS Foundation Trust, United Kingdom
TBC
15:45 - 17:30 Parallel Session: Paediatric Nephrology
Chairs:
Location: Hall 1B
Clinical and basic science aspects of tubular disease
Professor Elena Levtchenko, University Hospitals Leuven, Belgium
Rituximab and plasma exchange does not prevent disease recurrence in high risk FSGS following living donor transplantation
Dr Mohan Shenoy, Royal Manchester Children's Hospital, United Kingdom
Clinical and basic science aspects of glomerular disease; a focus on insulin resistance
Prof Richard Coward, University of Bristol, United Kingdom
A Retrospective Case Series 1996-2014 of Simple Renal Cysts in Children in a tertiary paediatric centre
Dr Sarah Roy, Alder Hey Children's Hospital, United Kingdom
CERTAIN paediatric renal transplant registry
Professor Burkhard Tönshoff, Heidelberg University Hospital, Germany
Improvement of patient and parent/carer experience through high quality information: Results of the infoKID evaluation
Dr Jan Dudley, Bristol Royal Hospital for Children, United Kingdom
15:45 - 17:30 Parallel Session: Regenerative Medicine
Chairs:
Location: Hall 1C
Title TBC
Professor Ton Rabelink, Leiden University Medical Centre, Netherlands
An overview of regenerative medicine therapies and their ability to ameliorate renal injury in rodents with kidney disease
Professor Trish Murray, University of Liverpool, United Kingdom
Cell-based regenerative medicine therapies for improving the viability of extended criteria donor kidneys
Marc Clancy, NHS Greater Glasgow and Clyde, United Kingdom
Generating mini-kidneys in vitro using stem cell technology
Professor Jamie Davies, University of Edinburgh, United Kingdom
The potential of macrophage-based therapies for resolving inflammation and promoting renal regeneration
Professor Jeremy Hughes, University of Edinburgh, United Kingdom
Inhibiting fibrosis and promoting renal regeneration in rodent models using antisense technology
Dr Claire Sharpe, King's College London, United Kingdom
17:30 - 18:00 Special Session: Summary of the Day
Location: Hall 1A
This meeting has been supported by Chiesi through purchase of exhibition stand space only.